Restless Legs Syndrome

Willis-Ekbom Disease (Restless Legs Syndrome)

Symptoms include:

  • U= urge to move the legs
  • R= rest induces symptoms
  • G= getting active brings relief
  • E= evening brings worse symptoms

What can be mistaken for RLS?

  • Positional Discomfort
  • Muscle Cramps
  • Arthritis
  • Neuropathy
  • Hypnic Jerks

What conditions are associated with RLS?

  • Iron Deficiency (very common cause)
  • Pregnancy
  • Renal Failure
  • Peripheral Neuropathy
  • Lumbar Spine Disease

Which drugs can cause or worsen RLS?

  • Nicotine
  • Caffeine
  • Antidepressants (TCA/SSRI)
  • Antihistamines
  • Dopamine Antagonists (ie: Metoclopramide, Compazine)

Why care about RLS?

  • Twice the odds of developing cardiovascular disease
  • Quality of life severely impacted
  • Can significantly disrupt sleep
  • Painful
  • Increases the risk of developing anxiety and depression
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